多肽合成丨中间体 Caspofungin 卡泊芬净 CAS号：162808-62-0

名称：卡泊芬净Caspofungin

CAS号：162808-62-0

序列：(4R,5S)-5-((2-aminoethyl)amino)-n2-(10,12-dimethyltetradecanoyl)-4-hydroxy-l-ornithyl-l-threonyl-trans-4-hydroxy-l-prolyl-(s)-4-hydroxy-4-(p-hydroxyphenyl)-l-threonyl-threo-3-hydroxy-l-ornithyl-trans-3-hydroxy-l-proline cyclic (1->6) disulfide

分子式：C52H88N10O15

分子量：1093.33

纯度：>98.0%

来源：合成

MSDS和COA：可提供

详细信息：Caspofungin是抗虫基棘齿脂肽的乙酸盐盐，是从真菌Glarea lozoyensis的发酵产物的半伴随性衍生的。Caspofungin抑制1,3-β-葡聚糖合酶，导致β（1,3）-D-葡聚糖的合成降低（真菌细胞壁的重要组成部分），真菌细胞壁的削弱和真菌细胞壁破裂。该药物对抗曲霉和念珠菌物种具有活性。

注：仅用于研究

Name: Caspofungin

CAS No. : 162808-62-0

Sequence: (4R,5S)-5-((2-aminoethyl)amino)-n2-(10,12-dimethyltetradecanoyl)-4-hydroxy-l-ornithyl-l-threonyl-trans-4-hydroxy-l-prolyl-(s)-4-hydroxy-4-(p-hydroxyphenyl)-l-threonyl-threo-3-hydroxy-l-ornithyl-trans-3-hydroxy-l-proline cyclic (1->6) disulfide

Molecular formula: C52H88N10O15

Molecular weight : 1093.33

Purity: >98.0%

Source: synthetic

MSDS and COA: available

Details: Caspofungin is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.

*note：Only for research

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